Postdoc in E. coli platform strain development

Danmarks Tekniske Universitet

Hørsholm, 1 stilling

We are seeking a talented postdoctoral researcher to join platform strain development efforts in the core flow facility (iLoop) at the Novo Nordisk Foundation Center for Biosustainability (DTU Biosustain) at the Technical University of Denmark (DTU).



Job description

The successful candidate will be working in a small project team focused on the development and characterization of strains with enhanced chemical and stress tolerance with the goal of achieving improved cell factories.



The postdoctoral position will more specifically focus on complementing our activities in generation and characterization of strains of E. coli evolved for growth on high concentrations of chemical products, and will involve a variety of experimental work to assign causative mutations and to determine biochemical mechanisms of tolerance. Tolerant host strains will also be metabolically engineered and tested for the production of compounds of interest.



Qualifications

Candidates should possess a PhD degree in chemical or biochemical engineering, biotechnology, biochemistry, molecular biology, or another relevant field.



Successful candidates will:

•Have extensive knowledge in the areas of metabolic engineering, synthetic biology, industrial microbiology, and/or strain physiology

•Have strong molecular biology skills, including experience with genome engineering and molecular cloning

•Exhibit strong data analysis and interpretation skills

•Be effective at working in a team

•Be able to communicate orally and in writing at an advanced level in English



Preferred candidates will additionally have experience in one or more of the following: functional genomics (transcriptomics, proteomics, metabolomics, etc.), microbial cell culturing/fermentation, protein expression and mutagenesis, adaptive laboratory evolution, analytical chemistry, biochemical/cell assay development, and next generation sequencing technologies.



We offer

We offer an interesting and challenging job in an international environment focused on education, research, public sector consultancy, and innovation. We strive for academic excellence and collegial respect and freedom tempered by responsibility. DTU is a leading technical university in northern Europe and benchmarks with the best universities in the world.



Salary and terms of employment

The appointment will be based on the collective agreement with the Confederation of Professional Associations (AC). The allowance will be agreed with the relevant union.



The period of employment is two years (preferably to begin January 2016).



The place of work will be the Novo Nordisk Foundation Center for Biosustainability (DTU Biosustain) at Kogle Allé 6, Hørsholm.



Further information

Further information can be requested from iLoop Project Leader Rebecca Lennen, rlen@biosustain.dtu.dk.



Application

Please submit your online application no later than 1 November 2015. Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link "Apply online," fill in the online application form, and attach all your materials in English in one PDF file. The file must include:

•Application (cover letter - explaining the applicant’s background and reasons for applying)

•Maximum 2-page curriculum vitae

•Diploma (an official translation into English)

•List of publications



Letters of recommendation may be included at the end of the application or sent directly to the referee.



Applications and enclosures received after the deadline will not be considered.



All interested candidates irrespective of age, gender, disability, race, religion or ethnic background are encouraged to apply.



The Novo Nordisk Foundation Center for Biosustainability is an international research center at the Technical University of Denmark funded by a grant of 1.1 billion DKK from the Novo Nordisk Foundation. The Center conducts research in metabolic engineering of cell factories, in silico systems biology and bioinformatics with the purpose of developing new processes and technologies that can support a more sustainable bio-based production of valuable chemicals in the future. The Center brings together some of the world's leading researchers in the field and possesses the advanced equipment and facilities required for achieving its ambitious research goals. Impact on society by innovation has a high priority and the Center collaborates worldwide with biotech companies and chemical industries to facilitate the dissemination and exploitation of its results. Additional information can be found at <a href='javascript:openLinkWindow("http://www.biosustain.dtu.dk")' "="" data-cke-saved-href='javascript:openLinkWindow("http://www.biosustain.dtu.dk")'>http://www.biosustain.dtu.dk.



DTU is a technical university providing internationally leading research, education, innovation and public service. Our staff of 5,800 advance science and technology to create innovative solutions that meet the demands of society; and our 10,300 students are being educated to address the technological challenges of the future. DTU is an independent academic university collaborating globally with business, industry, government, and public agencies.