We are looking for 1-2 highly motivated postdoctoral fellows to join the Mucosal Immunology Group headed by Professor William Agace at the Division of Experimental and Translational Immunology, Department of Health Technology, Technical University of Denmark. The successful candidate will join a superb team of international researchers within the newly established NovoNordisk Foundation challenge grant-funded ‘Center for Intestinal Immune Regulation (CIIR)’. CIIR comprises of 4 collaborating teams (Agace, DTU; McCoy, Calgary (Canada); Bendtsen, Hvidovre hospital; Rønn-Larsen, DTU) whose combined expertise in mucosal immunology, gastroenterology, microbiota-host interactions, bioinformatics and state-of-the-art animal models aims to identify intestinal immune-stromal interactions important in intestinal homeostasis and in inflammatory bowel disease (IBD).  In joining you will be part of a highly vibrant and cross-disciplinary team of researchers at the international forefront of mucosal immunology research.

Responsibilities and qualifications
Your project is to identify immune-stromal interactions that are important for maintaining intestinal immune homeostasis and in the setting of inflammation promote immune mediated pathology. For this you will utilize state-of-the-art transgenic mouse models to modulate intestinal stromal-immune interactions and assess downstream consequences on intestinal homeostasis and disease (the latter using infection/inflammation models).  You will combine the above with scRNA-seq, CITE-seq, and spatial proteomics/transcriptomics analysis as well as in vitro co-culture techniques to perform mode of action studies. The project is multi-disciplinary and will involve close collaborations with participating bioinformaticians as well as researchers analyzing human intestinal immune compartments in health and IBD. The work is also expected to include some teaching and/or supervision of students within the laboratory.

You must hold a PhD degree or equivalent in immunology, be highly motivated, have the ability to work independently but also enjoy contributing and working within a team.  The successful candidates will have documented experience in mucosal immunology, working with transgenic animal models, mouse colony maintenance and in depth analysis of murine intestinal tissues including cell isolation, multi-color flow cytometry and cell sorting and intestinal disease models. Additional experience with spatial transcriptomics/proteomics scRNA-seq and organ cultures will be considered a merit.

We offer
DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility.

Salary and terms of employment
The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union.

The period of employment is 3 years full time with a starting date of 1 January 2023 (or according to mutual agreement). 

You can read more about career paths at DTU here

Further information
Further information please contact William Agace (wiag@dtu.dk).

Home page: Experimental and Translational Immunology research group

If you are applying from abroad, you may find useful information on working in Denmark and at DTU at DTU – Moving to Denmark.

Application procedure
Your complete online application must be submitted no later than 31 October 2022 (Danish time). Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link "Apply online", fill out the online application form, and attach all your materials in English in one PDF file. The file must include:

  • Application (cover letter)
  • CV
  • Academic Diplomas (MSc/PhD – in English)
  • List of publications
  • A one page summary documenting experiences/training of relevance to the job description

Applications received after the deadline will not be considered.

All interested candidates irrespective of age, gender, disability, race, religion or ethnic background are encouraged to apply.

DTU Health Tech engages in research, education, and innovation base on technical and natural science for the healthcare sector. The Healthcare sector is a globally expanding market with demands for the most advanced technological solutions. DTU Health Tech creates the foundation for companies to develop new and innovative services and products which benefit people and create value for society. DTU Health Tech’s expertise spans from imaging and biosensor techniques, across digital health and biological modelling, to biopharma technologies. The department has a scientific staff of about 210 persons, 140 PhD students and a technical/administrative support staff of about 160 persons, of which a large majority contributes to our research infrastructure and related commercial activities.

Technology for people
DTU develops technology for people. With our international elite research and study programmes, we are helping to create a better world and to solve the global challenges formulated in the UN’s 17 Sustainable Development Goals. Hans Christian Ørsted founded DTU in 1829 with a clear vision to develop and create value using science and engineering to benefit society. That vision lives on today. DTU has 13,400 students and 5,800 employees. We work in an international atmosphere and have an inclusive, evolving, and informal working environment. DTU has campuses in all parts of Denmark and in Greenland, and we collaborate with the best universities around the world.

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About company

The Danish job market is booming and many sectors are facing skills shortages. Therefore, there are many sectors with good job opportunities one of them is Life Science. The Danish life sciences industry, comprising almost 1.500 life sciences companies and approximately 47.300 employees, contribute considerably to both R&D, economic progress and employment in Denmark. Subsidiaries of most of the major international life sciences companies are already present in Denmark, employing over one fourth of all employees in the Danish life sciences industry. In Denmark, there is a long-standing tradition for efficient public-private partnerships in areas such as development and testing… Read more